Nexus Pharmacy
As interest in medical weight loss continues to grow, many people across Nottingham are asking about Wegovy. If you have heard about this injectable treatment and are wondering what to expect, understanding the potential side effects is an important part of making an informed decision.
At Nexus Pharmacy in Nottingham, our weight loss clinic team is here to guide you through your options clearly and responsibly. Whether you are just starting to explore Wegovy or are already on treatment, contact us or book an appointment to speak with our team.
Knowing what side effects are possible, how common they are, and when to seek help means you can approach your weight loss journey with greater confidence.
What Is Wegovy?
Wegovy (semaglutide 2.4mg) is a once-weekly injectable medication licensed in the UK for chronic weight management in adults. It belongs to a class of medicines known as GLP-1 receptor agonists, which work by mimicking a natural hormone that regulates appetite and food intake.
Wegovy is prescribed alongside a reduced-calorie diet and increased physical activity for adults with a BMI of 30 or above, or 27 or above with a weight-related health condition.
It is not a quick fix, but for many patients it can be a highly effective tool as part of a wider lifestyle programme.
Common Wegovy Side Effects
The most frequently reported Wegovy side effects relate to the digestive system. These tend to be most noticeable when starting treatment or when the dose is increased, and they often improve over time.
Common side effects may include:
- Nausea
- Vomiting
- Diarrhoea
- Constipation
- Stomach pain or discomfort
- Indigestion or heartburn
- Bloating or wind
- Reduced appetite
- Belching
Most patients find these symptoms are mild to moderate and settle within the first few weeks as the body adjusts to the medication.
Less Common But Important Side Effects
Some patients may experience side effects that are less frequent but worth being aware of. These include:
- Headaches
- Dizziness or light-headedness
- Fatigue
- Injection site reactions such as redness, bruising or itching
- Increased heart rate
- Hair loss (reported by some patients during weight loss)
- Low blood sugar, particularly if taken alongside other diabetes medications
It is important to tell your healthcare provider about any symptoms you experience, even if they do not appear on this list.
Side Effects at a Glance: Frequency Table
| Side Effect | Frequency | Typically Resolves? |
|---|---|---|
| Nausea | Very common | Yes, often within weeks |
| Diarrhoea | Very common | Yes, usually short term |
| Constipation | Common | Often improves with hydration |
| Vomiting | Common | Yes, typically short lived |
| Headache | Common | Usually temporary |
| Fatigue | Less common | Often improves over time |
| Increased heart rate | Less common | Discuss with your provider |
| Injection site reaction | Less common | Usually mild and brief |
Serious Side Effects: When To Seek Help
While serious side effects are rare, it is essential to know what to look out for. Stop using Wegovy and seek urgent medical attention if you experience:
- Severe abdominal pain that does not ease, which could indicate pancreatitis
- Symptoms of a serious allergic reaction, including swelling of the face, lips, tongue or throat, difficulty breathing, or a rapid heartbeat
- Changes in vision or signs of diabetic retinopathy worsening
- Symptoms of gallbladder problems such as severe upper abdominal pain, fever or yellowing of the skin
- Thoughts of self-harm or significant mood changes
If you are ever unsure, do not hesitate to contact a healthcare professional promptly.
Tips for Managing Common Side Effects
Many patients find that making small adjustments helps reduce the impact of Wegovy side effects, particularly in the early weeks of treatment.
▶ Managing Nausea
- Eat smaller, more frequent meals rather than large portions
- Avoid rich, fatty or highly spiced foods, especially when starting treatment
- Stay upright for at least 30 minutes after eating
- Ginger tea or ginger biscuits may help settle the stomach
- Eat slowly and chew food thoroughly
▶ Managing Constipation
- Increase your daily fluid intake, aiming for at least 6 to 8 glasses of water
- Include more fibre-rich foods such as fruits, vegetables, wholegrains and pulses
- Stay physically active where possible
- Speak to your pharmacist if constipation persists, as a gentle laxative may help
▶ Managing Injection Site Reactions
- Rotate injection sites regularly between the abdomen, thigh and upper arm
- Allow the pen to reach room temperature before injecting
- Do not inject into areas that are tender, bruised or scarred
- Ask our team to review your injection technique if reactions continue
Who May Not Be Suitable for Wegovy?
Wegovy is not appropriate for everyone. A clinical assessment is required before starting treatment. You may not be suitable if you:
- Have a personal or family history of medullary thyroid carcinoma
- Have a condition called Multiple Endocrine Neoplasia syndrome type 2
- Are pregnant or breastfeeding
- Have a history of pancreatitis
- Have severe gastrointestinal disease
- Are under 18 years of age
Our weight loss clinic conducts a full consultation before recommending any treatment, ensuring that Wegovy is the right choice for you.
FAQs About Wegovy Side Effects
How long do Wegovy side effects last?
For most patients, side effects are at their worst during the dose escalation phase. They typically improve within the first four to eight weeks as the body adjusts.
Does everyone experience nausea on Wegovy?
Not everyone will experience nausea, though it is the most commonly reported side effect. Eating smaller meals and avoiding fatty foods can help minimise it.
Can Wegovy cause hair loss?
Some patients notice temporary hair thinning during rapid weight loss. This is generally related to the calorie deficit rather than the medication itself and usually resolves over time.
Is it safe to take Wegovy long term?
Wegovy has been evaluated in clinical trials over several years. For most eligible patients, long term use is considered safe under medical supervision.
What should I do if side effects are affecting my daily life?
Contact your healthcare provider. There may be adjustments to your dose schedule or additional support available to help you manage.
Can I drink alcohol while taking Wegovy?
Alcohol is not directly contraindicated, but it can worsen nausea and contribute to low blood sugar. It is advisable to limit alcohol intake during treatment.
Start Your Weight Loss Journey in Nottingham
Understanding side effects is a sensible first step before beginning any new treatment, be it Wegovy or Mounjaro. For the majority of patients, side effects are manageable and improve with time, and the benefits of sustained weight loss can be significant for long term health.
At Nexus Pharmacy in Nottingham, our team is here to support you at every stage, from your first consultation through to ongoing monitoring and advice. If you would like to find out whether Wegovy could be suitable for you, contact us, call 0115 727 0999, email hello@nexuspharmacy.co.uk, or book an appointment with our weight loss clinic today.